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2013
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Publié par
Date de parution
15 février 2013
Nombre de lectures
6
EAN13
9780702053382
Langue
English
Poids de l'ouvrage
5 Mo
Underwood’s Pathology (formerly General and Systematic Pathology) is an internationally popular and highly acclaimed textbook, written and designed principally for students of medicine and the related health sciences. Pathology is presented in the context of modern cellular and molecular biology and contemporary clinical practice. After a clear introduction to basic principles, it provides comprehensive coverage of disease mechanisms and the pathology of specific disorders ordered by body system. An unrivalled collection of clinical photographs, histopathology images and graphics complement the clear, concise text.
For this sixth edition, the entire book has been revised and updated. Well liked features to assist problem-based learning – including body diagrams annotated with signs, symptoms and diseases and a separate index of common clinical problems – have been retained and refereshed.
Additional value is provided by the complementary online version – hosted on studentconsult.com - which includes the complete, fully searchable text, downloadable images, clinical case studies and a revised, interactive self-assessment section to check your understanding and aid exam preparation. This all combines to make Underwood’s an unsurpassed learning package in this fascinating and most central medical specialty.
Publié par
Date de parution
15 février 2013
Nombre de lectures
6
EAN13
9780702053382
Langue
English
Poids de l'ouvrage
5 Mo
Underwood’s Pathology: a Clinical Approach
with STUDENT CONSULT Access
Sixth Edition
Simon S. Cross, MD FRCPath
Professor of Diagnostic Histopathology and Honorary Consultant Histopathologist, Academic Unit of Pathology, Department of Neuroscience, Faculty of Medicine, Dentistry & Health, The University of Sheffield, Sheffield, UK
Table of Contents
Cover image
Title page
Copyright
Preface
Acknowledgements
International Advisers
Contributors
Index of Patient Symptoms
Part 1: Basic Pathology
Chapter 1: What is pathology?
History of pathology
Scope of pathology
Techniques of pathology
Learning pathology
Making diagnoses
Pathology and populations
Chapter 2: What is disease?
What is disease?
Characteristics of disease
Nomenclature of disease
Principles of disease classification
Epidemiology
Chapter 3: What causes disease?
Causes of disease
Genetic abnormalities in disease
Environmental factors
Infective agents
Part 2: Disease Mechanisms
Chapter 4: Disorders of growth, differentiation and morphogenesis
Definitions
Normal growth, differentiation and morphogenesis
Abnormalities of growth, differentiation and morphogenesis
Chapter 5: Responses to cellular injury
Cellular injury
Repair and regeneration
Injury due to ionising radiation
Chapter 6: Disorders of metabolism and homeostasis
Inborn errors of metabolism
Acquired metabolic disorders
Metabolic consequences of malnutrition
Obesity
Trace elements and disease
Tissue depositions
Chapter 7: Ischaemia, infarction and shock
Non-thromboembolic vascular insufficiency
Thromboembolic vascular occlusion
Infarction
Shock
Chapter 8: Immunology and immunopathology
Defence against infection
Key molecules
Structural organisation of the immune system
Functional organisation of the immune response
Non-specific effector mechanisms
Outcomes of immune responses
Immunodeficiency
Hypersensitivity reactions
Autoimmunity and autoimmune disease
Principles of organ transplantation
Chapter 9: Inflammation
Acute inflammation
Chronic inflammation
Chapter 10: Carcinogenesis and neoplasia
General characteristics of neoplasms (tumours)
Classification of tumours
Nomenclature of tumours
Biology of tumour cells
Carcinogenesis
Cellular and molecular events in carcinogenesis
Behaviour of tumours
Early detection of cancer by screening
Hallmarks
Chapter 11: Ageing and death
Theories of ageing
Death
Chapter 12: How do pathologists help patient care?
Types of laboratory tests
Specialised tests
Autopsies
Part 3: Systematic Pathology
Chapter 13: Cardiovascular system
Diseases of the arteries and other vessels
Cardiac disease
Chapter 14: Respiratory tract
Diseases of infancy and childhood
Nasal passages, middle ear and sinuses
Larynx
The lungs
Chapter 15: Alimentary system
Mouth, teeth, pharynx and salivary glands
Oesophagus
Stomach
Intestine
Appendix
Anus and anal canal
Chapter 16: Liver, biliary system and pancreas
Common clinical problems from liver and biliary system disease
Liver
Biliary system
Paediatric liver disease
pancreas
Chapter 17: Endocrine system
Pituitary
Pineal gland
Adrenals
Thyroid
Parathyroids
Endocrine pancreas
Chapter 18: Breast
Common clinical problems from breast disease
Normal structure and function
Clinical features of breast lesions
Diagnostic methods
Inflammatory conditions
Proliferative conditions of the breast
Benign tumours
Breast carcinoma
Other tumours
Chapter 19: Female genital tract
Common clinical problems from female genital tract disease
Normal development
Vulva
Non-neoplastic epithelial disorders
Neoplastic epithelial disorders
Vagina and cervix
Cervical squamous neoplasia
Glandular neoplasia of the cervix
Other malignant tumours
Uterine corpus
Congenital abnormalities
The normal endometrium and menstrual cycle
Abnormalities of the endometrium
Abnormalities of the myometrium
Ovary
Ovarian cysts
Ovarian stromal hyperplasia and stromal luteinisation
Endometriosis
Ovarian neoplasms
Fallopian tubes
Pathology of pregnancy
Hydatidiform mole
Pathology of the full-term placenta
Pathology of the umbilical cord and membranes
Pathology of the placental bed
Ectopic pregnancy
Maternal death
Chapter 20: Urinary and male genital tracts
Urinary calculi
Renal tumours
Ureters
Bladder
Tumours of the bladder
Prostate gland
Penis and scrotum
Urethra
Testis
Epididymis and cord
Chapter 21: Kidney diseases
Common clinical problems from kidney disease
Introduction
Functions of the kidney
Glomerular diseases
Tubular disorders
Vascular diseases
Urinary tract obstruction and infections
Cystic renal diseases
Congenital anomalies
Renal transplantation
Chapter 22: Lymph nodes and extranodal lymphoid tissue, spleen and thymus
Lymph nodes
Spleen
Thymus
Chapter 23: Blood and bone marrow
Composition, production and functions of blood
Neoplastic disorders of the bone marrow
Disorders of blood coagulation and haemostasis
Chapter 24: Skin
Common clinical problems from skin disease
Normal structure and function
Clinical aspects of skin diseases
Disorders involving inflammatory and haemopoietic cells
Infections
Non-infectious inflammatory diseases
Epidermal cells
Melanocytes
Dermal vessels
Adnexa
Dermal connective tissues
Deposits
Cutaneous nerves
Behaviour and the skin
Toxins and the skin
Skin manifestations of internal and systemic disease
Chapter 25: Osteoarticular and connective tissues
Bone
Joints
Connective tissues
Chapter 26: Central and peripheral nervous systems
Central nervous system
Peripheral nervous system
Skeletal muscle
The eye
The ear
Glossary
Index
Copyright
© 2013 Elsevier Ltd. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions .
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).
First edition 1992
Second edition 1996
Third edition 2000
Fourth edition 2004
Fifth edition 2009
Sixth edition 2013
ISBN 978-0-7020-4672-8
International ISBN 978-0-7020-4673-5
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library
Library of Congress Cataloging in Publication Data
A catalog record for this book is available from the Library of Congress
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
Printed in China
Preface
Underwood’s Pathology has been written, designed and produced primarily for students of medicine and for those studying related health science subjects, such as biomedi