Hematology, Immunology and Infectious Disease: Neonatology Questions and Controversies E-Book , livre ebook

Hematology, Immunology and Infectious Disease
Neonatology Questions and Controversies
Second Edition

Robin K. Ohls, MD
Professor of Pediatrics, University of New Mexico; Associate Director, Pediatrics, Clinical Translational Science Center, University of New Mexico Health Sciences, Albuquerque, New Mexico

Akhil Maheshwari, MD
HAssociate Professor of Pediatrics and Pharmacology, Chief, Division of Neonatology, Director, Neonatology Fellowship Program, Director, Center for Neonatology and Pediatric Gastrointestinal Disease, University of Illinois at Chicago; Medical Director, Neonatology Intensive Care Unit and Intermediate Care Nursery, Children’s Hospital of University of Illinois, Chicago, Illinois
Saunders
Table of Contents
Cover image
Title page
Series page
Copyright
Contributors
Series Foreword
Preface
Chapter 1: Updated Information on Stem Cells for the Neonatologist
Chapter 2: Current Issues in the Pathogenesis, Diagnosis, and Treatment of Neonatal Thrombocytopenia
Chapter 3: The Role of Recombinant Leukocyte Colony-Stimulating Factors in the Neonatal Intensive Care Unit
Chapter 4: Nonhematopoietic Effects of Erythropoietin
Chapter 5: Why, When, and How Should We Provide Red Cell Transfusions and Erythropoiesis-Stimulating Agents to Support Red Cell Mass in Neonates?
Chapter 6: Diagnosis and Treatment of Immune-Mediated and Non–Immune-Mediated Hemolytic Disease of the Newborn
Chapter 7: Hematology and Immunology: Coagulation Disorders
Chapter 8: A Practical Approach to the Neutropenic Neonate
Chapter 9: What Evidence Supports Dietary Interventions to Prevent Infant Food Hypersensitivity and Allergy?
Chapter 10: Maternally Mediated Neonatal Autoimmunity
Chapter 11: CMV: Diagnosis, Treatment, and Considerations on Vaccine-Mediated Prevention
Chapter 12: Neonatal T Cell Immunity and Its Regulation by Innate Immunity and Dendritic Cells
Chapter 13: Breast Milk and Viral Infection
Chapter 14: Probiotics for the Prevention of Necrotizing Enterocolitis in Preterm Neonates
Chapter 15: The Ureaplasma Conundrum: Should We Look or Ignore?
Chapter 16: Control of Antibiotic-Resistant Bacteria in the Neonatal Intensive Care Unit
Chapter 17: Neonatal Fungal Infections
Chapter 18: The Use of Biomarkers for Detection of Early- and Late-Onset Neonatal Sepsis
Chapter 19: Chorioamnionitis and Its Effects on the Fetus/Neonate: Emerging Issues and Controversies
Index
Series page

Hematology, Immunology and Infectious Disease
Neonatology Questions and Controversies
Series Editor
Richard A. Polin, MD
Professor of Pediatrics
College of Physicians and Surgeons
Columbia University
Vice Chairman for Clinical and Academic Affairs, Department of Pediatrics
Director, Division of Neonatology
Morgan Stanley Children’s Hospital of NewYork-Presbyterian
Columbia University Medical Center
New York, New York
Other Volumes in the Neonatology Questions and Controversies Series
GASTROENTEROLOGY AND NUTRITION
HEMODYNAMICS AND CARDIOLOGY
NEPHROLOGY AND FLUID/ELECTROLYTE PHYSIOLOGY
NEUROLOGY
THE NEWBORN LUNG
Copyright

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HEMATOLOGY, IMMUNOLOGY AND INFECTIOUS DISEASE: NEONATOLOGY QUESTIONS AND CONTROVERSIES ISBN: 978-1-4377-2662-6
Copyright © 2012, 2008 by Saunders, an imprint of Elsevier Inc.
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Notices
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Library of Congress Cataloging-in-Publication Data
Hematology, immunology, and infectious disease : neonatology questions and controversies / [edited by Robin K. Ohls]. — 2nd ed.
  p. cm. — (Neonatology questions and controversies series)
 Includes bibliographical references and index.
 ISBN 978-1-4377-2662-6 (alk. paper)
 1. Neonatal hematology. 2. Newborn infants—Immunology. 3. Communicable diseases in newborn infants. I. Ohls, Robin K.
 RJ269.5.H52 2012
 618.92′01—dc23
2011053382
Senior Content Strategist: Stefanie Jewell-Thomas
Content Development Specialist: Lisa Barnes
Publishing Services Manager: Anne Altepeter
Team Manager: Hemamalini Rajendrababu
Project Manager: Siva Raman Krishnamoorthy
Design Direction: Ellen Zanolle
Printed in The United States of America
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Contributors

Jennifer L. Armstrong-Wells, MD
Director Perinatal and Hemorrhagic Stroke Programs Department of Pediatrics Section of Neurology Hemophilia and Thrombosis Center; Assistant Professor Pediatric Neurology University of Colorado Aurora, Colorado; Assistant Adjunct Professor Neurology University of California, San Francisco San Francisco, California Hematology and Immunology: Coagulation Disorders

Nader Bishara, MD
Attending Neonatologist Pediatrix Medical Group Huntington Memorial Hospital Pasadena, California The Use of Biomarkers for Detection of Early- and Late-Onset Neonatal Sepsis

L. Vandy Black, MD
Instructor, Division of Pediatric Hematology The Johns Hopkins University Baltimore, Maryland A Practical Approach to the Neutropenic Neonate

Suresh B. Boppana, MD
Professor, Pediatrics and Microbiology University of Alabama at Birmingham Birmingham, Alabama CMV: Diagnosis, Treatment, and Considerations on Vaccine-Mediated Prevention

Catalin S. Buhimschi, MD
Associate Professor, Director Perinatal Research Interim Division Director Maternal Fetal Medicine Obstetrics, Gynecology, and Reproductive Sciences Yale University School of Medicine; Interim Chief of Obstetrics Obstetrics, Gynecology, and Reproductive Sciences Yale New Haven Hospital New Haven, Connecticut Chorioamnionitis and Its Effects on the Fetus/Neonate: Emerging Issues and Controversies

Irina A. Buhimschi, MD, MMS
Associate Professor Obstetrics, Gynecology, and Reproductive Sciences Yale University School of Medicine New Haven, Connecticuit Chorioamnionitis and Its Effects on the Fetus/Neonate: Emerging Issues and Controversies

Robert D. Christensen, MD
Director of Research Women and Newborns Intermountain Healthcare Salt Lake City, Utah The Role of Recombinant Leukocyte Colony-Stimulating Factors in the Neonatal Intensive Care Unit

Misti Ellsworth, DO
Pediatric Infectious Disease San Antonio, Texas Neonatal Fungal Infections

Björn Fischler, MD, PhD
Associate Professor Pediatrics CLINTEC
Karolinska Institutet; Senior Consultant Pediatric Hepatology Pediatrics Karolinska University Hospital Stockholm, Sweden Breast Milk and Viral Infection

Marianne Forsgren, MD, PhD
Associate Professor of Virology Department of Clinical Microbiology Karolinska University Hospital, Huddinge Stockholm, Sweden Breast Milk and Viral Infection

Peta L. Grigsby, PhD
Assistant Scientist Division of Reproductive Sciences Oregon National Primate Research Center; Assistant Research Professor Department of Obstetrics and Gynecology Oregon Health and Science University Portland, Oregon The Ureaplasma Conundrum: Should We Look or Ignore?

Sandra E. Juul, MD, PhD
Professor, Pediatrics University of Washington; Professor, Pediatrics Seattle Children’s Hospital Seattle, Washington Nonhematopoietic Effects of Erythropoietin

David B. Lewis, MD
Professor and Chief, Division