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Neuroradiology: Key Differential Diagnoses and Clinical Questions equips you to make efficient, accurate diagnoses and prepare for imaging exams with hundreds of high-quality, unknown cases in neuroradiology. Drs. Juan Small and Pamela Schaefer draw upon Massachusetts General Hospital’s vast case collection to help you master the skills you need for interpreting imaging of the head, neck, brain, and spine.

  • Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.
  • Apply systematic pattern analysis techniques to distinguish similar-looking pathological entities from one another.
  • Avoid diagnostic pitfalls by recognizing significant variations in the clinical presentation of various diseases.
  • See how diagnostic ambiguities are resolved by viewing corresponding gross pathologic and histologic images.
  • Benefit from the volume and exceptional quality of Massachusetts General Hospital’s patient case load.

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17 septembre 2012

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NEURORADIOLOGY

Key Differential Diagnoses and Clinical Questions

JUAN E. SMALL, MD
Assistant Professor of Neuroradiology, Lahey Clinic, Tufts University School of Medicine, Burlington, Massachusetts

PAMELA W. SCHAEFER, MD
Associate Director of Neuroradiology, Clinical Director of MRI, Massachusetts General Hospital, Associate Professor of Radiology, Harvard Medical School, Boston, Massachusetts
1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
NEURORADIOLOGY: KEY DIFFERENTIAL DIAGNOSES AND CLINICAL QUESTIONS ISBN: 978-1-4377-1721-1
Copyright 2013 by Saunders, an imprint of Elsevier Inc.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the Publisher. Details on how to seek permission, further information about the Publisher s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions .
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
Library of Congress Cataloging-in-Publication Data
Small, Juan E.
Neuroradiology : key differential diagnoses and clinical questions / Juan E. Small, Pamela W. Schaefer.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-1-4377-1721-1 (hardcover : alk. paper)
I. Schaefer, Pamela W. II. Title.
[DNLM: 1. Diagnostic Techniques, Neurological-Case Reports. 2. Nervous System Diseases-radiography-Case Reports. 3. Diagnosis, Differential-Case Reports. 4. Neuroradiography-methods-Case Reports. WL 141]
617 .075--dc23 2012016008
Executive Content Strategist: Pamela Hetherington
Content Development Specialist: Margaret Nelson
Publishing Services Manager: Patricia Tannian
Project Manager: Carrie Stetz
Design Direction: Steven Stave
Dedication
This book is dedicated to my beautiful wife and best friend Kirstin. Thank you for helping me to understand the things that really matter in life, in ways I never could before we met. Without you, my life would be incomplete. I love you and cherish our life together .
And to my parents, Aurora and Richard. Without your support and unconditional love, none of my achievements would have been possible. Thank you for encouraging me to follow my heart .

Juan E. Small
This book is dedicated to my wonderful husband, Douglas Raines, and my beautiful daughter, Sarah Raines, who always give me unconditional love, support, and wisdom .

Pamela W. Schaefer
Section Editors

HUGH D. CURTIN, MD
Chief of Radiology Massachusetts Eye and Ear Infirmary Professor of Radiology Harvard Medical School Boston, Massachusetts

R. GILBERTO GONZALEZ, MD, PhD
Director of Neuroradiology Massachusetts General Hospital Professor of Radiology Harvard Medical School Boston, Massachusetts

HILLARY R. KELLY, MD
Neuroradiologist Massachusetts General Hospital Professor of Radiology Harvard Medical School Boston, Massachusetts

STUART R. POMERANTZ, MD
Associate Director of Neuro-CT Neuroradiologist Massachusetts General Hospital Harvard Medical School Boston, Massachusetts

PAMELA W. SCHAEFER, MD
Associate Director of Neuroradiology Clinical Director of MRI Massachusetts General Hospital Associate Professor of Radiology Harvard Medical School Boston, Massachusetts

JUAN E. SMALL, MD
Assistant Professor of Neuroradiology Lahey Clinic Tufts University School of Medicine Burlington, Massachusetts

TINA YOUNG-POUSSAINT, MD
Neuroradiologist Boston Children s Hospital Professor of Radiology Harvard Medical School Boston, Massachusetts
Contributors

JALIL AFNAN, MD
Clinical Associate Lahey Clinic Tufts University School of Medicine Burlington, Massachusetts

KENNETH S. ALLISON, MD
Instructor Harvard Medical School Clinical Assistant Massachusetts General Hospital Boston, Massachusetts

NINO BOALS, MD
Neuroradiology Fellow and Research Assistant Massachusetts General Hospital Boston, Massachusetts

FARGOL BOOYA, MD
Neuroradiology Fellow Massachusetts General Hospital Boston, Massachusetts

HUI J. JENNY CHEN, MD
Neuroradiology Fellow Massachusetts General Hospital Boston, Massachusetts

ROBERT CHEN, MD
Department of Radiology Massachusetts General Hospital Boston, Massachusetts

SAMI ERBAY, MD
Assistant Professor Lahey Clinic Tufts University School of Medicine Burlington, Massachusetts

JOHN FAGNOU, MD
Assistant Clinical Professor Diagnostic Imaging University of Calgary Calgary, Alberta, Canada

REZA FORGHANI, MD, PhD
Associate Chief Jewish General Hospital Assistant Professor of Radiology McGill University Montreal, Quebec, Canada

DANIEL THOMAS GINAT, MD
Neuroradiology Fellow Harvard Medical School Boston, Massachusetts

MAI-LAN HO, MD
Resident Scholar s Track Department of Radiology Beth Israel Deaconess Medical Center Boston, Massachusetts

LIANGGE HSU, MD
Assistant Professor Harvard Medical School Staff Neuroradiologist Brigham and Women s Hospital Boston, Massachusetts

SCOTT EDWARD HUNTER, MD
Neuroradiology Fellow Massachusetts General Hospital Boston, Massachusetts

JASON MICHAEL JOHNSON, MD
Neuroradiology Fellow Massachusetts General Hospital Boston, Massachusetts

HILLARY R. KELLY, MD
Neuroradiologist Massachusetts General Hospital Professor of RadiologyHarvard Medical School Boston, Massachusetts

GIRISH KORI, MD
Neuroradiology Fellow Massachusetts General Hospital Boston, Massachusetts

MYKOL LARVIE, MD, PhD
Instructor Harvard Medical School Radiologist Massachusetts General Hospital Boston, Massachusetts

GUL MOONIS, MD
Assistant Professor Beth Israel Deaconess Medical Center; Staff Radiologist Massachusetts Eye and Ear Infirmary Boston, Massachusetts

MICHAEL T. PREECE, MD
Department of Radiology Massachusetts General Hospital Boston, Massachusetts

AMMAR SARWAR, MD
Radiology Fellow Beth Israel Deaconess Medical Center Harvard Medical School Boston, Massachusetts

PAMELA W. SCHAEFER, MD
Associate Director of Neuroradiology Clinical Director of MRI Massachusetts General Hospital
Associate Professor of Radiology Harvard Medical School Boston, Massachusetts

SANTOSH KUMAR SELVARAJAN, MD
Neuroradiology Fellow Brigham and Women s Hospital Children s Hospital Boston Boston, Massachusetts

JUAN E. SMALL, MD
Assistant Professor of Neuroradiology Lahey Clinic Tufts University School of Medicine Burlington, Massachusetts

HENRY S. SU, MD, PhD
Neuroradiology Fellow Massachusetts General Hospital Clinical Fellow Harvard Medical School Boston, Massachusetts

KATHARINE TANSAVATDI, MD
Neuroradiology Fellow Massachusetts General Hospital Boston, Massachusetts

NICHOLAS A. TELISCHAK, MD
Radiology Resident Beth Israel Deaconess Medical Center Department of Radiology Harvard Medical School Boston, Massachusetts

BRIAN ZIPSER, MD
Neuroradiology Fellow Massachusetts General Hospital Boston, Massachusetts
Preface
This book is based on the premise that one of the most powerful learning techniques for imaging interpretation is the presentation of unknown cases. Although primarily a case book of unknowns, the style is intentionally out of the ordinary, with several unknown cases presented together. The choice of this format presented several challenges, but we believe that the added value is well worth the investment. We are convinced that side-by-side comparison and contrast of similar-appearing lesions is essential for building an invaluable visual database for imaging interpretation. It is with the hope of increasing our diagnostic specificity that the format of the book was chosen.

Juan E. Small, MD

Pamela W. Schaefer, MD
Acknowledgments
We would like to gratefully acknowledge Lo

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