#p53

Transfert des gènes p53 et pten par vectorisation non virale : effet pro-apoptotique et potentialisation de la réponse cellulaire au cétuximab, P53 and pten transfer gene using non viral vector : pro-apoptotic effect and potentiation of cell response to cetuximab

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Transfert des gènes p53 et pten par vectorisation non virale : effet pro-apoptotique et potentialisation de la réponse cellulaire au cétuximab, P53 and pten transfer gene using non viral vector : pro-apoptotic effect and potentiation of cell response to cetuximab

Sanae Bouali

Transfert des gènes p53 et pten par vectorisation non virale : effet pro-apoptotique et potentialisation de la réponse cellulaire au cétuximab, P53 and pten transfer gene using non viral vector : pro-apoptotic effect and potentiation of cell response to cetuximab

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Transfert des gènes p53 et pten par vectorisation non virale : effet pro-apoptotique et potentialisation de la réponse cellulaire au cétuximab, P53 and pten transfer gene using non viral vector : pro-apoptotic effect and potentiation of cell response to cetuximab

Sanae Bouali

195 pages

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HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas

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HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas

Sosin, Siddiqi Aisha, Abrams Judith, Al-Katib, Burger, Mohammad

HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas

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HDM2 antagonist MI-219 (spiro-oxindole), but not Nutlin-3 (cis-imidazoline), regulates p53 through enhanced HDM2 autoubiquitination and degradation in human malignant B-cell lymphomas

Sosin, Siddiqi Aisha, Abrams Judith, Al-Katib, Burger, Mohammad

18 pages

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Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line

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Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line

Zhou Yingqi, Li Gang, Ji Yuan, Liu Chen, Zhu Jingping, Lu Yanjun, Lu

Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line

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Cytoplasmic p21 induced by p65 prevents doxorubicin-induced cell death in pancreatic carcinoma cell line

Zhou Yingqi, Li Gang, Ji Yuan, Liu Chen, Zhu Jingping, Lu Yanjun, Lu

10 pages

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Association of Ataxia Telangiectasia Mutated (ATM) gene mutation/deletion with Rhabdomyosarcoma

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Association of Ataxia Telangiectasia Mutated (ATM) gene mutation/deletion with Rhabdomyosarcoma

Zhang Peilin, Bhakta, Puri Pier, Newbury, Feramisco, Wang

Association of Ataxia Telangiectasia Mutated (ATM) gene mutation/deletion with Rhabdomyosarcoma

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Association of Ataxia Telangiectasia Mutated (ATM) gene mutation/deletion with Rhabdomyosarcoma

Zhang Peilin, Bhakta, Puri Pier, Newbury, Feramisco, Wang

10 pages

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Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

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Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

Hewedi, Radwan, Shash

Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

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Diagnostic value of progesterone receptor and p53 expression in uterine smooth muscle tumors

Hewedi, Radwan, Shash

6 pages

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Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

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Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

Gallagher, Heffron, Laios Alexandros, O'Toole, Ffrench Brendan, Smyth, Elbaruni, Spillane, Sheils, O'Leary, Martin, Flavin

Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

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Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

Gallagher, Heffron, Laios Alexandros, O'Toole, Ffrench Brendan, Smyth, Elbaruni, Spillane, Sheils, O'Leary, Martin, Flavin

11 pages

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Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr

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Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr

Fedrigo, Grivicich Ivana, Schunemann, Chemale, Santos Daiane, Jacovas Thais, Boschetti, Jotz, Filho Aroldo, Ad

Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr

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Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr

Fedrigo, Grivicich Ivana, Schunemann, Chemale, Santos Daiane, Jacovas Thais, Boschetti, Jotz, Filho Aroldo, Ad

10 pages

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The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis

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The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis

Morissette, Parent Julie, Milot, Milot Julie

The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis

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The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis

Morissette, Parent Julie, Milot, Milot Julie

8 pages

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Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma

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Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma

Liu Qingjun, Mier, Panka

Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma

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Differential modulatory effects of GSK-3β and HDM2 on sorafenib-induced AIF nuclear translocation (programmed necrosis) in melanoma

Liu Qingjun, Mier, Panka

15 pages

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The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway

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The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway

Chen Zheng-Lin, Gu Ping-Qing, Liu Kangsheng, Su Ya-Juan, Gao Ling-Juan, Gao

The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway

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The globular heads of the C1q receptor regulate apoptosis in human cervical squamous carcinoma cells via a p53-dependent pathway

Chen Zheng-Lin, Gu Ping-Qing, Liu Kangsheng, Su Ya-Juan, Gao Ling-Juan, Gao

12 pages

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Temporally distinct roles for tumor suppressor pathways in cell cycle arrest and cellular senescence in Cyclin D1-driven tumor

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Temporally distinct roles for tumor suppressor pathways in cell cycle arrest and cellular senescence in Cyclin D1-driven tumor

Zalzali Hasan, Harajly Mohamad, Abdul-Latif Lina, El-Chaar Nader, Dbaibo Ghassan, Skapek, Saab, Saab Raya

Temporally distinct roles for tumor suppressor pathways in cell cycle arrest and cellular senescence in Cyclin D1-driven tumor

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Temporally distinct roles for tumor suppressor pathways in cell cycle arrest and cellular senescence in Cyclin D1-driven tumor

Zalzali Hasan, Harajly Mohamad, Abdul-Latif Lina, El-Chaar Nader, Dbaibo Ghassan, Skapek, Saab, Saab Raya

12 pages

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Expression of anti-apoptotic protein survivin and tumor suppressor p53 protein in patients with pulmonary carcinoma

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Expression of anti-apoptotic protein survivin and tumor suppressor p53 protein in patients with pulmonary carcinoma

Halasová E, Adamkov M, Kavcová E, Matáková T, Musák L, Vybohová D, Janícková M, Mistuna D, Singliar, Singliar A

Expression of anti-apoptotic protein survivin and tumor suppressor p53 protein in patients with pulmonary carcinoma

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Expression of anti-apoptotic protein survivin and tumor suppressor p53 protein in patients with pulmonary carcinoma

Halasová E, Adamkov M, Kavcová E, Matáková T, Musák L, Vybohová D, Janícková M, Mistuna D, Singliar, Singliar A

4 pages

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Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)

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Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)

Muenyi, States, Masters, Fan, Helm

Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)

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Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)

Muenyi, States, Masters, Fan, Helm

11 pages

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Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts

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Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts

Storozhuk Yaryna, Sanli Toran, Hopmans, Schultz Carrie, Farrell Tom, Cutz Jean-Claude, Wright James, Singh Gurmit, Tsakiridis, Tsakiridis Theodoros, Steinberg

Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts

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Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts

Storozhuk Yaryna, Sanli Toran, Hopmans, Schultz Carrie, Farrell Tom, Cutz Jean-Claude, Wright James, Singh Gurmit, Tsakiridis, Tsakiridis Theodoros, Steinberg

11 pages

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Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways

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Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways

Rashid Ayesha, Liu Caiqiong, Sanli Toran, Tsiani Evangelia, Singh Gurmit, Bristow, Dayes Ian, Lukka Himu, Wright James, Tsakiridis, Tsakiridis Theodoros

Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways

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Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways

Rashid Ayesha, Liu Caiqiong, Sanli Toran, Tsiani Evangelia, Singh Gurmit, Bristow, Dayes Ian, Lukka Himu, Wright James, Tsakiridis, Tsakiridis Theodoros

12 pages

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Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells

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Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells

Ajay, Meena, Bhat

Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells

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Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells

Ajay, Meena, Bhat

11 pages

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Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways

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Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways

Choi Hyeong, Seo Hye-Sook, Um Jae-Young, Shin Yong, Ko Seong-Gyu, Ko, Kim Ji

Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways

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Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways

Choi Hyeong, Seo Hye-Sook, Um Jae-Young, Shin Yong, Ko Seong-Gyu, Ko, Kim Ji

12 pages

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Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells

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Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells

Yang Mingzhen, Chen Zhongjiao, Chen An, Li Shuhui, Hu Chuanmin, Hu, Fang Yuan, Peng Li

Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells

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Interferon regulatory factor 4 binding protein is a novel p53 target gene and suppresses cisplatin-induced apoptosis of breast cancer cells

Yang Mingzhen, Chen Zhongjiao, Chen An, Li Shuhui, Hu Chuanmin, Hu, Fang Yuan, Peng Li

13 pages

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Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)

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Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)

Fei Fei, Lim Min, Schmidhuber Sabine, Moll Jürgen, Groffen John, Heisterkamp, Heisterkamp Nora

Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)

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Treatment of human pre-B acute lymphoblastic leukemia with the Aurora kinase inhibitor PHA-739358 (Danusertib)

Fei Fei, Lim Min, Schmidhuber Sabine, Moll Jürgen, Groffen John, Heisterkamp, Heisterkamp Nora

12 pages

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Glycerol as a chemical chaperone enhances radiation-induced apoptosis in anaplastic thyroid carcinoma cells

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Glycerol as a chemical chaperone enhances radiation-induced apoptosis in anaplastic thyroid carcinoma cells

Ohnishi Ken, Ota Ichiro, Yane Katsunari, Takahashi Akihisa, Yuki Kazue, Emoto Mie, Hosoi Hiroshi, Ohnishi, Ohnishi Takeo

Glycerol as a chemical chaperone enhances radiation-induced apoptosis in anaplastic thyroid carcinoma cells

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Glycerol as a chemical chaperone enhances radiation-induced apoptosis in anaplastic thyroid carcinoma cells

Ohnishi Ken, Ota Ichiro, Yane Katsunari, Takahashi Akihisa, Yuki Kazue, Emoto Mie, Hosoi Hiroshi, Ohnishi, Ohnishi Takeo

5 pages

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