Scleroderma, An Issue of Rheumatic Disease Clinics , livre ebook

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206

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English

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Ebooks

2015

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206

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2015

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Scleroderma, or systemic sclerosis, is a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases. Hardening of the skin is one of the most visible manifestations of the disease. It’s estimated that about 300,000 Americans have scleroderma. About one third of those people have the systemic form of scleroderma. Since scleroderma presents with symptoms similar to other autoimmune diseases, diagnosis is difficult. This issue will cover: The Genetic Basis of SSc: Genetics, Epigenetics, Mechanisms of Pathogenesis – linking fibrosis, vasculopathy and immune dysregulation, The Role of Autoantibodies in Diagnosis and Prognosis/survival; Managing Raynaud’s phenomenon and ischemic ulcers, managing SSc Lung Disease, Monitoring for and Managing Pulmonary Arterial Hypertension, and many more!


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Date de parution

12 novembre 2015

Nombre de lectures

0

EAN13

9780323393553

Langue

English

Poids de l'ouvrage

1 Mo

Clinics Review Articles Rheumatic Disease Clinics of North America
Scleroderma
Maureen D. Mayes, MD, MPH Division of Rheumatology and Clinical Immunogenetics, University of Texas - Houston Medical School, Houston, TX, USA
I SSN 0889-857X VO L UM E 41 • NUM BER 3 • AUG UST 2015
Elsevier
Table of Contents
Cover image
Title page
Copyright-Page
Contributors Consulting Editor Editor Authors
Forthcoming Issues Forthcoming Issues Recent Issues
Foreword: Systemic Sclerosis
Preface: Systemic Sclerosis
Genetics, Epigenetics, and Genomics of Systemic Sclerosis Key points Introduction
Initial evidence of the genetic influence in systemic sclerosis
Genetic study modalities
Known genetic associations with systemic sclerosis
Other sources of genetic variation
Gene expression profiling Summary
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Alternate Text