Principles of Pulmonary Medicine E-Book , livre ebook

Principles of Pulmonary Medicine
Sixth Edition

Steven E. Weinberger, MD, FACP
Executive Vice President and Chief Executive Officer, American College of Physicians, Adjunct Professor of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, Senior Lecturer on Medicine, Harvard Medical School, Boston, Massachusetts

Barbara A. Cockrill, MD
Pulmonary Vascular Disease Center, Brigham and Women’s Hospital, Assistant Professor of Medicine, Harvard Medical School, Boston, Massachusetts

Jess Mandel, MD, FACP
Professor of Medicine, Associate Dean for Undergraduate Medical Education, University of California San Diego School of Medicine, La Jolla, California
Table of Contents
Cover image
Title page
Copyright
Dedication
Introduction to the Sixth Edition
Online Contents
Chapter 1: Pulmonary Anatomy and Physiology: The Basics
Anatomy
Physiology
Abnormalities in Gas Exchange
Chapter 2: Presentation of the Patient with Pulmonary Disease
Dyspnea
Cough
Hemoptysis
Chest Pain
Chapter 3: Evaluation of the Patient with Pulmonary Disease
Evaluation on a Macroscopic Level
Evaluation on a Microscopic Level
Assessment on a Functional Level
Chapter 4: Anatomic and Physiologic Aspects of Airways
Structure
Function
Chapter 5: Asthma
Etiology and Pathogenesis
Pathology
Pathophysiology
Clinical Features
Diagnostic Approach
Treatment
Chapter 6: Chronic Obstructive Pulmonary Disease
Etiology and Pathogenesis
Pathology
Pathophysiology
Clinical Features
Diagnostic Approach and Assessment
Treatment
Chapter 7: Miscellaneous Airway Diseases
Bronchiectasis
Cystic Fibrosis
Upper Airway Disease
Chapter 8: Anatomic and Physiologic Aspects of the Pulmonary Parenchyma
Anatomy
Physiology
Chapter 9: Overview of Diffuse Parenchymal Lung Diseases
Pathology
Pathogenesis
Pathophysiology
Clinical Features
Diagnostic Approach
Treatment
Chapter 10: Diffuse Parenchymal Lung Diseases Associated with Known Etiologic Agents
Diseases Caused by Inhaled Inorganic Dusts
Hypersensitivity Pneumonitis
Drug-Induced Parenchymal Lung Disease
Radiation-Induced Lung Disease
Chapter 11: Diffuse Parenchymal Lung Diseases of Unknown Etiology
Idiopathic Pulmonary Fibrosis
Other Idiopathic Interstitial Pneumonias
Pulmonary Parenchymal Involvement Complicating Connective Tissue Disease
Sarcoidosis
Miscellaneous Disorders Involving the Pulmonary Parenchyma
Chapter 12: Anatomic and Physiologic Aspects of the Pulmonary Vasculature
Anatomy
Physiology
Chapter 13: Pulmonary Embolism
Etiology and Pathogenesis
Pathology
Pathophysiology
Clinical Features
Diagnostic Evaluation
Treatment
Chapter 14: Pulmonary Hypertension
Pathogenesis
Pathology
Pathophysiology
Clinical Features
Diagnostic Features
Specific Disorders Associated with Pulmonary Hypertension
Chapter 15: Pleural Disease
Anatomy
Physiology
Pleural Effusion
Pneumothorax
Chapter 16: Mediastinal Disease
Anatomic Features
Mediastinal Masses
Pneumomediastinum
Chapter 17: Anatomic and Physiologic Aspects of Neural, Muscular, and Chest Wall Interactions with the Lungs
Respiratory Control
Respiratory Muscles
Chapter 18: Disorders of Ventilatory Control
Primary Neurologic Disease
Cheyne-Stokes Breathing
Control Abnormalities Secondary to Lung Disease
Sleep Apnea Syndrome
Chapter 19: Disorders of the Respiratory Pump
Neuromuscular Disease Affecting the Muscles of Respiration
Diaphragmatic Disease
Diseases Affecting the Chest Wall
Chapter 20: Lung Cancer: Etiologic and Pathologic Aspects
Etiology and Pathogenesis
Pathology
Chapter 21: Lung Cancer: Clinical Aspects
Clinical Features
Diagnostic Approach
Principles of Therapy
Bronchial Carcinoid Tumors
Malignant Mesothelioma
Solitary Pulmonary Nodule
Chapter 22: Lung Defense Mechanisms
Physical or Anatomic Factors
Antimicrobial Peptides
Phagocytic and Inflammatory Cells
Adaptive Immune Responses
Failure of Respiratory Defense Mechanisms
Augmentation of Respiratory Defense Mechanisms
Chapter 23: Pneumonia
Etiology and Pathogenesis
Pathology
Pathophysiology
Clinical Features
Diagnostic Approach
Therapeutic Approach: General Principles and Antibiotic Susceptibility
Initial Management Strategies Based on Clinical Setting of Pneumonia
Intrathoracic Complications of Pneumonia
Respiratory Infections Associated with Bioterrorism
Chapter 24: Tuberculosis and Nontuberculous Mycobacteria
Etiology and Pathogenesis
Definitions
Pathology
Pathophysiology
Clinical Manifestations
Diagnostic Approach
Principles of Therapy
Nontuberculous Mycobacteria
Chapter 25: Miscellaneous Infections Caused by Fungi and Pneumocystis
Fungal Infections
Pneumocystis Infection
Chapter 26: Pulmonary Complications in the Immunocompromised Host
Acquired Immunodeficiency Syndrome (AIDS)
Pulmonary Complications in Non-HIV Immunocompromised Patients
Chapter 27: Classification and Pathophysiologic Aspects of Respiratory Failure
Definition of Respiratory Failure
Classification of Acute Respiratory Failure
Presentation of Gas Exchange Failure
Pathogenesis of Gas Exchange Abnormalities
Clinical and Therapeutic Aspects of Hypercapnic/Hypoxemic Respiratory Failure
Chapter 28: Acute Respiratory Distress Syndrome
Physiology of Fluid Movement in Alveolar Interstitium
Etiology
Pathogenesis
Pathology
Pathophysiology
Clinical Features
Diagnostic Approach
Treatment
Chapter 29: Management of Respiratory Failure
Goals of Supportive Therapy for Gas Exchange
Mechanical Ventilation
Selected Aspects of Therapy for Chronic Respiratory Failure
Chapter 30: Sample Problems Using Respiratory Equations
Answers
Chapter 31: Pulmonary Function Tests: Guidelines for Interpretation and Sample Problems
Analysis of Pulmonary Function Tests
Answers
Chapter 32: Arterial Blood Gases: Guidelines for Interpretation and Sample Problems
Analysis of Acid-Base Status
Analysis of Oxygenation
Sample Problems
Answers
Index
Copyright

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PRINCIPLES OF PULMONARY MEDICINE ISBN: 978-1-4557-2532-8
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Library of Congress Cataloging-in-Publication Data
Weinberger, Steven E.
Principles of pulmonary medicine / Steven E. Weinberger, Barbara A. Cockrill, Jess Mandel.—6th ed.
  p. ; cm.
 Includes bibliographical references and index.
 ISBN 978-1-4557-2532-8 (pbk. : alk. paper)
 I. Cockrill, Barbara A. II. Mandel, Jess. III. Title.
 [DNLM: 1. Lung Diseases. 2. Respiration Disorde