Pharmacology E-Book , livre ebook
903
pages
English
Ebooks
2012
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903
pages
English
Ebooks
2012
Obtenez un accès à la bibliothèque pour le consulter en ligne En savoir plus
Publié par
Date de parution
14 novembre 2012
Nombre de lectures
12
EAN13
9781455702787
Langue
English
Poids de l'ouvrage
11 Mo
Pharmacology, 4th Edition helps you master the "must-know" concepts in this subject and how they apply to everyday clinical problem solving and decision making. This concise yet comprehensive text clearly explains and illustrates challenging concepts and helps you retain the material - from course exams and the USMLE Step 1 right through to clinical practice.
- Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.
- Quickly reference essential information thanks to abundant tables throughout, and drug classification boxes at the beginning of each chapter.
- See how pharmacology applies to practice with real-world case studies.
- Prepare for exams with self-assessment questions at the end of each chapter.
- Understand complex concepts visually with the aid of superb full-color illustrations.
- Access the complete contents online at www.studentconsult.com, along with an additional glossary, chapter-by-chapter summaries and case studies, a full list of featured drugs, 150 USMLE-style questions, animations, and more.
- Learn the latest pharmacologic mechanisms and applications with new and updated drug information throughout.
- Be aware of new "off label" uses, including important FDA regulations.
Publié par
Date de parution
14 novembre 2012
Nombre de lectures
12
EAN13
9781455702787
Langue
English
Poids de l'ouvrage
11 Mo
Pharmacology
FOURTH EDITION
George M. Brenner, PhD
Professor Emeritus of Pharmacology, Oklahoma State University, Center for Health
Sciences, Tulsa, Oklahoma
Craig W. Stevens, PhD
Professor of Pharmacology, Oklahoma State University, Center for Health Sciences, Tulsa,
OklahomaTable of Contents
Cover image
Title page
Copyright
Preface
Section I: Principles of Pharmacology
Chapter 1: Introduction to Pharmacology
Pharmacology and Related Sciences
Drug Sources and Preparations
Routes of Drug Administration
Drug Names
Summary of Important Points
Chapter 2: Pharmacokinetics
Overview
Drug Absorption
Drug Distribution
Drug Biotransformation
Drug Excretion
Quantitative Pharmacokinetics
Single-Dose Pharmacokinetics
Continuous-Dose and Multiple-Dose Kinetics
Summary of Important PointsChapter 3: Pharmacodynamics
Overview
Nature of Drug Receptors
Drug-Receptor Interactions
Dose-Response Relationships
Summary of Important Points
Chapter 4: Drug Development and Safety
Overview
Drug Development
The Investigational New Drug Application
Federal Drug Laws and Regulations
Adverse Effects of Drugs
Drug Interactions
Factors Affecting Drug Safety and Efficacy
Summary of Important Points
Section II: Autonomic and Neuromuscular Pharmacology
Chapter 5: Introduction to Autonomic and Neuromuscular Pharmacology
Overview
Anatomy and Physiology of the Peripheral Nervous System
Neurotransmitters and Receptors
Neurotransmission and Sites of Drug Action
Summary of Important Points
Chapter 6: Acetylcholine Receptor Agonists
Overview of Cholinergic Pharmacology
Classification of Acetylcholine Receptor Agonists
Direct-Acting Acetylcholine Receptor Agonists
Indirect-Acting Acetylcholine Receptor AgonistsSummary of Important Points
Chapter 7: Acetylcholine Receptor Antagonists
Overview
Muscarinic Receptor Antagonists
Nicotinic Receptor Antagonists
Summary of Important Points
Chapter 8: Adrenoceptor Agonists
Overview
Adrenoceptors
Signal Transduction
Classification of Adrenoceptor Agonists
Indirect-Acting Adrenoceptor Agonists
Mixed-Acting Adrenoceptor Agonists
Summary of Important Points
Chapter 9: Adrenoceptor Antagonists
Overview
α-Adrenoceptor Antagonists
β-Adrenoceptor Antagonists
α- and β-Adrenoceptor Antagonists
Summary of Important Points
Section III: Cardiovascular, Renal, and Hematologic Pharmacology
Chapter 10: Antihypertensive Drugs
Overview
Diuretics
Sympatholytic Drugs
Angiotensin Inhibitors
VasodilatorsThe Management of Hypertension
Summary of Important Points
Chapter 11: Antianginal Drugs
Overview
Vasodilators
β-Adrenoceptor Antagonists
Drugs that Modify Myocardial Metabolism
Management of Angina Pectoris
Summary of Important Points
Chapter 12: Drugs for Heart Failure
Overview
Positively Inotropic Drugs
Vasodilators
β-Adrenoceptor Antagonists
Aldosterone Antagonists
Diuretics
Management of Heart Failure
Summary of Important Points
Chapter 13: Diuretics
Overview
Nephron Function and Sites of Drug Action
Diuretic Agents
Management of Edema
Summary of Important Points
Chapter 14: Antiarrhythmic Drugs
Overview
Sodium Channel Blockers
Other Antiarrhythmic DrugsManagement of Supraventricular Arrhythmias
Management of Ventricular Arrhythmias
Summary of Important Points
Chapter 15: Drugs for Hyperlipidemia
Overview
Drugs for Hypercholesterolemia
Drug Combinations
Summary of Important Points
Chapter 16: Anticoagulant, Antiplatelet, and Fibrinolytic Drugs
Overview
Blood Coagulation
Anticoagulant Drugs
Antiplatelet Drugs
Summary of Important Points
Chapter 17: Hematopoietic Drugs
Overview
Drugs
Summary of Important Points
Section IV: Central Nervous System Pharmacology
Chapter 18: Introduction to Central Nervous System Pharmacology
Overview
Neurotransmission in the Central Nervous System
Mechanisms of Drug Action
Neuronal Systems in the Central Nervous System
Summary of Important Points
Chapter 19: Sedative-Hypnotic and Anxiolytic DrugsOverview
Anxiety Disorders
Sleep Disorders
Sedative-Hypnotic Drugs
Summary of Important Points
Chapter 20: Antiepileptic Drugs
Overview
Treatment of Seizure Disorders
The Management of Seizure Disorders
Summary of Important Points
Chapter 21: Local and General Anesthetics
Overview
Local Anesthetics
Specific Agents
General Anesthetics
Inhalational Anesthetics
Specific Agents
Parenteral Anesthetics
Summary of Important Points
Chapter 22: Psychotherapeutic Drugs
Overview
Schizophrenia
Affective Disorders
Antidepressant Drugs
Mood-Stabilizing Drugs
Central Nervous System Stimulants
Summary of Important Points
Chapter 23: Opioid Analgesics and AntagonistsOverview
Pain and Analgesic Agents
Pain Pathways
Opioid Peptides and Receptors
Opioid Drugs
Specific Agents
The Treatment of Pain
Summary of Important Points
Chapter 24: Drugs for Neurodegenerative Diseases
Overview
Parkinson Disease
Huntington Disease
Alzheimer Disease
Multiple Sclerosis
Amyotrophic Lateral Sclerosis
Antispastic Agents
Summary of Important Points
Chapter 25: Drugs of Abuse
Overview
Central Nervous System Depressants
Central Nervous System Stimulants
Other Psychoactive Drugs
Prescription Drug Abuse
Steroid Drug Abuse
Inhalant Abuse
Management of Drug Abuse
Summary of Important Points
Section V: Pharmacology of the Respiratory and Other SystemsChapter 26: Autacoid Drugs
Overview
Histamine and Related Drugs
Antihistamine Drugs
Serotonin and Related Drugs
Eicosanoids and Related Drugs
Eicosanoid Drugs
Endothelin-1 Antagonists
Summary of Important Points
Chapter 27: Drugs for Respiratory Tract Disorders
Overview
Antiinflammatory Drugs
Bronchodilators
Management of Asthma
Antitussives
Expectorants
Management of Rhinitis
Summary of Important Points
Chapter 28: Drugs for Gastrointestinal Tract Disorders
Overview
Drugs for Peptic Ulcer Disease
Treatment of Helicobacter Pylori Infection
Drugs for Inflammatory Bowel Diseases
Gastrointestinal Motility Disorders
Drugs for Constipation
Antidiarrheal Agents
Antiemetics
Summary of Important PointsChapter 29: Drugs for Headache Disorders
Overview
Characteristics and Pathogenesis of Migraine Headaches
Drugs for Migraine Headaches
Drugs for Migraine Prevention
Drugs for Migraine Termination
Guidelines for Managing Migraine Headaches
Characteristics and Treatment of Cluster Headaches
Characteristics and Treatment of Tension Headaches
Summary of Important Points
Chapter 30: Drugs for Pain, Inflammation, and Arthritic Disorders
Overview
Rheumatoid Arthritis
Osteoarthritis
Gout
Nonsteroidal Antiinflammatory Drugs
Specific Agents
Disease-Modifying Antirheumatic Drugs
Drugs for the Treatment of Gout
Summary of Important Points
Section VI: Endocrine Pharmacology
Chapter 31: Hypothalamic and Pituitary Drugs
Overview
Anterior Pituitary Hormones
Posterior Pituitary Hormones
Summary of Important Points
Chapter 32: Thyroid DrugsOverview
Thyroid Disorders
Thyroid Hormone Preparations
Antithyroid Agents
Summary of Important Points
Chapter 33: Adrenal Steroids and Related Drugs
Overview
Synthesis and Secretion of Adrenal Steroids
Physiologic Effects of Adrenal Steroids
Corticosteroid Drugs
Mineralocorticoids
Glucocorticoids
Adrenal Androgens
Corticosteroid Synthesis Inhibitors
Corticosteroid Receptor Antagonists
Summary of Important Points
Chapter 34: Drugs Affecting Fertility and Reproduction
Overview
Estrogens and Progestins
Contraceptives
Antiestrogens
Antiprogestins
Androgens
Antiandrogens
Summary of Important Points
Chapter 35: Drugs for Diabetes Mellitus
Overview
Insulin PreparationsOther Antidiabetic Agents
Dopamine Agonist
Management of Diabetes
Summary of Important Points
Chapter 36: Drugs Affecting Calcium and Bone
Overview
Pharmacologic Agents
Management of Calcium and Bone Disorders
Summary of Important Points
Section VII: Chemotherapy
Chapter 37: Principles of Antimicrobial Chemotherapy
Overview
Classification of Antimicrobial Drugs
Antimicrobial Activity
Microbial Sensitivity and Resistance
Selection of Antimicrobial Drugs
Combination Drug Therapy
Prophylactic Therapy
Summary of Important Points
Chapter 38: Inhibitors of Bacterial Cell Wall Synthesis
Overview
β-Lactam Antibiotics
Other Bacterial Cell Wall Synthesis Inhibitors
Summary of Important Points
Chapter 39: Inhibitors of Bacterial Protein Synthesis
Overview
Sites of Drug ActionDrugs That Affect the 30S Ribosomal Subunit
Drugs That Affect the 50S Ribosomal Subunit
Summary of Important Points
Chapter 40: Quinolones, Antifolate Drugs, and Other Antimicrobial Agents
Overview
Antifolate Drugs
Fluoroquinolones
Other Antibacterial Drugs
Summary of Important P
