Hacker & Moore's Essentials of Obstetrics and Gynecology E-Book , livre ebook

Hacker and Moore's ESSENTIALS OF OBSTETRICS AND GYNECOLOGY
Fifth Edition

Neville F. Hacker, MD
Professor of Gynaecologic Oncology Conjoint, University of New South Wales Director, Gynaecological Cancer Centre Royal Hospital for Women Sydney, Australia

Joseph C. Gambone, DO, MPH, Executive Editor
Professor Emeritus of Obstetrics and Gynecology David Geffen School of Medicine at UCLA Attending Physician, Ronald Reagan UCLA Medical Center Clinical Professor of Obstetrics and Gynecology Western University of Health Sciences College of Osteopathic Medicine of the Pacific Residency Education Consultant Arrowhead Regional Medical Center San Bernardino, California

Calvin J. Hobel, MD
Miriam Jacobs Chair in Maternal-Fetal Medicine Cedars-Sinai Medical Center Professor of Obstetrics and Gynecology Professor of Pediatrics David Geffen School of Medicine at UCLA Los Angeles, California
SAUNDERS
Front Matter

Hacker and Moore's Essentials of Obstetrics and Gynecology
5th Edition
Neville F. Hacker, MD
Professor of Gynaecologic Oncology, Conjoint, University of New South Wales
Director, Gynaecological Cancer Centre, Royal Hospital for Women, Sydney, Australia
Joseph C. Gambone, DO, MPH, Executive Editor
Professor Emeritus of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA
Attending Physician, Ronald Reagan UCLA Medical Center, Clinical Professor of Obstetrics and Gynecology, Western University of Health Sciences, College of Osteopathic Medicine of the Pacific
Residency Education Consultant, Arrowhead Regional Medical Center, San Bernardino, California
Calvin J. Hobel, MD
Miriam Jacobs Chair in Maternal-Fetal Medicine, Cedars-Sinai Medical Center, Professor of Obstetrics and Gynecology, Professor of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California
Copyright

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HACKER AND MOORE'S ESSENTIALS OF OBSTETRICS AND GYNECOLOGY ISBN: 978-1-4160-5940-0
International Edition ISBN: 978-0-8089-2416-6
Copyright © 2010, 2004, 1998, 1992, 1986 by Saunders, an imprint of Elsevier Inc.
All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier's Rights Department: phone: (+1) 215 239 3804 (US) or (+44) 1865 843830 (UK); fax: (+44) 1865 853333; e-mail: healthpermissions@elsevier.com . You may also complete your request on-line via the Elsevier website at http://www.elsevier.com/permissions .

Notice
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the Editors assume any liability for any injury and/or damage to persons or property arising out of or related to any use of the material contained in this book.
Library of Congress Cataloging-in-Publication Data
Hacker, Neville F.
Hacker and Moore's essentials of obstetrics and gynecology/Neville F. Hacker, Joseph C. Gambone, Calvin J. Hobel. — 5th ed. p.; cm.
Rev. ed. of: Essentials of obstetrics and gynecology/[edited by] Neville F. Hacker, J. George Moore, Joseph C. Gambone. 4th ed. c2004.
Includes bibliographical references and index.
ISBN 978–1–4160–5940–0
1. Gynecology. 2. Obstetrics. I. Gambone, Joseph C. II. Hobel, Calvin J. III. Essentials of obstetrics and gynecology. IV. Title. V. Title: Essentials of obstetrics and gynecology.
[DNLM: 1. Obstetrics. 2. Genital Diseases, Female. 3. Pregnancy Complications. WQ 100 H118h 2010]
RG101.E87 2010
618—dc22 2008025860
Acquisitions Editor: James Merritt
Developmental Editor: Christine Abshire
Publishing Services Manager: Linda Van Pelt
Design Direction: Gene Harris
Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2
Dedication
This edition is dedicated to our wives, Estelle Hacker, Marge (Morris) Gambone, and Marsha Lynn Hobel.
Their understanding and support for the time and effort required to complete this project was essential .
Contributors

Carolyn J. Alexander, MD, Assistant Clinical Professor, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Associate Director, Obstetrics and Gynecology Residency Program, Attending Physician, Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California
Puberty and Disorders of Pubertal Development; Amenorrhea, Oligomenorrhea, and Hyperandrogenic Disorders

Ricardo Azziz, MD, MPH, MBA, Professor and Vice-Chair, Department of Obstetrics and Gynecology, Professor, Department of Medicine, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Chair, Department of Obstetrics and Gynecology, Director, Center for Androgen-Related Disorders, Cedars-Sinai Medical Center, Los Angeles, California
Puberty and Disorders of Pubertal Development; Amenorrhea, Oligomenorrhea, and Hyperandrogenic Disorders

Richard A. Bashore, MD, Professor Emeritus, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California
Fetal Surveillance During Labor; Uterine Contractility and Dystocia

Jonathan S. Berek, MD, MMS, Professor and Chair, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California
Ovarian Cancer; Gestational Trophoblastic Neoplasia

Narender N. Bhatia, MD, Professor, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California, Chief of Urogynecology, Director of Fellowship in Female Pelvic Medicine and Reconstructive Surgery, Harbor-UCLA Medical Center, Torrance, California
Genitourinary Dysfunction: Pelvic Organ Prolapse, Urinary Incontinence, and Infections

Richard P. Buyalos, Jr., MD, Attending Physician, Ronald Reagan UCLA Medical Center, University of California at Los Angeles, Los Angeles, California, Attending Physician, Community Memorial Hospital, Ventura, California, Attending Physician, Los Robles Hospital, Thousand Oaks, California
Puberty and Disorders of Pubertal Development

Lony C. Castro, MD, Professor and Chair, Department of Obstetrics and Gynecology, Western University of Health Sciences, College of Osteopathic Medicine of the Pacific, Pomona, California, Maternal Fetal Medicine Specialist, Obstetrics and Gynecology, Arrowhead Regional Medical Center, San Bernardino, California, Maternal Fetal Medicine Specialist, Obstetrics and Gynecology, Riverside County Regional Medical Center, Riverside, California
Hypertensive Disorders of Pregnancy; Rhesus Isoimmunization; Common Medical and Surgical Conditions Complicating Pregnancy

Ozlem Equils, MD, Associate Professor, Pediatrics, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Attending Physician, Pediatric Infectious Diseases, Cedars-Sinai Medical Center, Los Angeles, California
Maternal Physiologic and Immunologic Adaptation to Pregnancy

Bruce B. Ettinger, MD, MPH, Health Facilities Licensing and Certification Division, Los Angeles County Department of Public Health Los Angeles, California
Family and Intimate Partner Violence, and Sexual Assault

Michael L. Friedlander, MBChB, PhD, Conjoint Professor of Medicine, University of New South Wales, Director, Department of Medical Oncology, Prince of Wales Hospital, Consultant Medical Oncologist, Gynecological Cancer Centre, Royal Hospital for Women, Sydney, Australia
Breast Disease: A Gynecologic Perspective

Robert H. Hayashi, MD, J. Robert Willson Professor of Obstetrics, Emeritus, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan
Obstetric Hemorrhage and Puerperal Sepsis; Uterine Contractility and Dystocia

Daniel A. Kahn, MD, PhD, Clinical Instructor, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California
Maternal Physiologic and Immunologic Adaptation to Pregnancy

Matthew Kim, MD, Assistant Professor, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Chief of Inpatient Obstetrics, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California
Obstetric Hemorrhage and Puerperal Sepsis

Brian J.. Koos, MD, DPhil, Professor, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California
Maternal Physiolog