Statistical inference of complex demographic models in Drosophila melanogaster and two wild tomato species [Elektronische Ressource] / Stefan Laurent

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Biologie

Statistical inference
of complex demographic models
in Drosophila melanogaster and two wild tomato species
Stefan Laurent
München 2010Erklärung:
Diese Dissertation wurde im Sinne von §12 der Promotionsordnung von Prof. Dr. Stephan betreut.
Ich erkl äre hiermit, dass die Dissertation nicht einer anderen Pr üfungskommission vorgelegt worden
ist und dass ich mich nicht anderweitig einer Doktorpr üfung ohne Erfolg unterzogen habe.
Ehrenwörtliche Versicherung:
Ich versichere ferner hiermit ehrenw örtlich, dass die vorgelegte Dissertation von mir selbstst ändig,
ohne unerlaubte Hilfe angefertigt wurde.
München, .....................
Stefan Laurent
Dekan: Prof. Dr. Benedikt Grothe
1. Gutachter: Prof. Dr. Wolfgang Stephan
2. Gutachter: Prof. Dr. John Parsch
Dissertation eingereicht am: 2 Dezember 2010
Datum der Disputation: 14 Januar 2011Declaration of contributions as a coauthor
In this dissertation I present the work of my doctoral research from June 2007 to November 2010. It
is organized in three chapters. All of them are the results of collaborations with other scientists.
For the work presented in the first chapter, Wolfgang Stephan, Laurent Excoffier and I
designed the study. Annegret Werzner, Anne Wilkens and I collected the data. Laurent Excoffier
and I conducted the statistical analysis. I developed the computational tools required for the analysis.
I did the writing and Wolfgang Stephan and Laurent Excoffier did the revisions. This chapter has
been accepted for publication pending minor revisions under the following title:
Laurent SJY, Werzner A, Excoffier L, Stephan W. 2011. Approximate Bayesian analysis of
Drosophila melanogaster polymorphism data reveals a recent colonization of Southeast Asia . Mol
Biol Evol (accepted with minor revisions)
For the second chapter Aurelien Tellier and myself designed the study and conducted the
analysis. I developed the computational tools for the analysis. Hilde Lainer collected the data for the
specieswide sample. Aurelien Tellier wrote most of the manuscript and I wrote the sections about
the ABC analysis. The manuscript was revised by myself and Wolfgang Stephan. A paper is in
preparation that contains parts of this chapter.For the third chapter Pavlos Pavlidis and myself designed the study and did the writing. Pavlos
Pavlidis did the programming. This paper has been published under the title:
*Pavlidis P, *Laurent S, Stephan W. 2010. msABC: a modification of Hudson's ms to facilitate
multilocus ABC analysis. Mol Ecol Resour 10:723−727. (*contributed equally)Statistical inference
of complex demographic models
in Drosophila melanogaster and two wild tomato species
Dissertation
an der Fakult ät f ür Biologie
der LudwigMaximiliansUniversit ät
München
vorgelegt von
Stefan Laurent
aus Br üssel
München, den 30.11.2010À Marie