DNA hybrid materials consisting of oligonucleotides and organic molecules [Elektronische Ressource] : synthesis, characterization and applications / Diana Milena Anaya
178
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English
Documents
2010
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178
pages
English
Documents
2010
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Publié par
Publié le
01 janvier 2010
Nombre de lectures
20
Langue
English
Poids de l'ouvrage
16 Mo
Publié par
Publié le
01 janvier 2010
Nombre de lectures
20
Langue
English
Poids de l'ouvrage
16 Mo
‘DNA Hybrid Materials Consisting of
Oligonucleotides and Organic Molecules:
Synthesis, Characterization and Applications’
Dissertation
zur Erlangung des Grades
“Doktor der Naturwissenchaften”
am Fachbereich
Chemie, Pharmazie und Geowissenschaften
der Johannes Gutenberg-Universität Mainz
Diana Milena Anaya
geb. in Bogotá, Kolumbien
Mainz 2010
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Dekan:
1. Berichterstatter:
2. Berichterstatter:
Tag der mündlichen Prüfung:
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Dedicated to my parents
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“Science knows no country, because knowledge
belongs to humanity, and is the torch which
illuminates the world.”
(Louis Pasteur )
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9 TABLE OF CONTENTS
LIST OF ABBREVIATIONS ...............................................................................13
Chapter 1
INTRODUCTION ................................................................................................17
1.1 DNA fundamentals.......................................................................................18
1.2 DNA as a construction material for nanoarchitectures .................................25
1.3 DNA-based hybrid materials ........................................................................29
1.4 Summary......................................................................................................32
1.5 References...................................................................................................34
Chapter 2
MOTIVATION AND OBJECTIVES.....................................................................39
Chapter 3
AGGREGATION OF DOUBLE STRANDED DNA INDUCED BY AROMATIC
π-SYSTEMS.......................................................................................................43
3.1 Introduction ..................................................................................................43
3.2 Preparation of dsDNA-PDI hybrids ..............................................................44
3.3 Analysis on surface by Atomic Force Microscopy (AFM) .............................46
3.4 Native polyacrylamide gel electrophoresis (PAGE) Analysis .......................48
3.5 Fluorescence correlation spectroscopy (FCS) study of DNA-PDI hybrids in
.solution .........................................................................................................49
3.6 Photophysical study of DNA-PDI hybrids.....................................................52
3.7 Conclusions .................................................................................................55
3.8 Experimental Section ...................................................................................57
3.9 References...................................................................................................66
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