Modelling heterogeneity in nucleotide sequence evolution
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31
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Simon Whelan Modelling heterogeneity in nucleotide sequence evolution Isaac Newton Institute Supported by:
Voir
- evolution interesting
- heterogeneity can
- evolution
- substitutions empirical models
- popular models
- markov model
- misspecification can confuse
- real sequence
- cause popular
Modelling heterogeneity in nucleotide sequence evolution
Simon Whelan
Supported by:
Isaac Newton Institute
i.
ii.
iii.
iv.
Talk outline
Introduction: what is spatial and temporal heterogeneity?
A temporal hidden Markov model of sequence evolution
Characterizing heterogeneity in real sequence data
Heterogeneity and the genetic code
i.
ii.
iii.
iv.
Talk outline
Introduction: what is spatial and temporal heterogeneity?
A temporal hidden Markov model of sequence evolution
Characterizing heterogeneity in real sequence data
Heterogeneity and the genetic code
